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Stock Code: 002675
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Date [2014-07-18 09:46]【 】Times


 
Product Name: heparin sodium
English Name: heparin sodium
Product Code: abbreviation of English name, HS
Product grade: ch.p/ep/usp/bp/ep6/crude product
Heparin sodium is a kind of glucosamine sulfate sodium salt. It is a mixture of molecules with different molecular weight. It has a linear chain structure composed of hexasaccharide or Octasaccharide repeat units. Disaccharide trisulfate is the main disaccharide unit of heparin. After complete hydrolysis, D-glucosamine, D-glucuronic acid, l-aiduronic acid, acetic acid and sulfuric acid were obtained.

It is an interactive polymer of α - D-glucosamine (N-sulfated, O-sulfated or N-acetylated) and uronic acid (α - l-iduronic acid, β - D-glucuronic acid) bound by glycosidic chains. Some of these components have the property of prolonging coagulation time.

It exists in mammalian tissues and can be prepared from bovine lungs or small intestinal mucosa of pigs, cattle and sheep. The extracted animals must meet the requirements for healthy animals for human use, and all biological and procurement stages must be monitored by the quality management system. The production process has been verified by virus inactivation, which can remove harmful pollutants.

Heparin sodium is a white or nearly white powder, which has the properties of moisture absorption, water solubility and optical rotation. It has a characteristic absorption peak at 185-220nm and an infrared characteristic absorption peak at 890cm-1940cm-1. The determination of the absorption value of 1210-1150cm-1 can be used for rapid determination.
 
GMP certificate of SFDA: Lu i0415
European CEP certificate: heparin sodium r1-cep 2003-197-rev02,
The GMP certificate of BSG in Hamburg, Germany: WEL / 020409 / gmp-yan,
FDA DMF registration number: 18355,
Japan MF registration number (EP standard): 218mf10695,
Indian registration number (IP / BP / USP standard): bd-544,
Russian registration number: 016111 / 01,
Russian registration number: 016111 / 01
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